P-1: The Impact of Gasoline Vapor Inhalation on Serum Levels of Testosterone in Male Rats

s:1080:"Background: Studies have shown that gasoline vapor influences many physiological aspects of body. The present study was exerted to evaluate the effects of gasoline vapor inhalation on serum levels of testosterone in male rats. Materials and Methods: Male Wistar rats were randomly divided into control, gasoline vapor receiving for 1hour, 2 hours and 3 hours/day. After 10 weeks, blood samples were collected using cardiac puncture method. Following serum collection, testosterone level was measured by radioimmunoassay method. Data were statistically analyzed and compared between groups using "one way- ANOVA". Results: The results indicated that serum testosterone level was not significantly changed in animals receiving gasoline vapor for 1 hour per day; however, it was significantly decreased in gasoline vapor receiving animals (2 hours or 3 hours/day) compared with control animals (p<0.01). Conclusion: Our findings indicate that chronic inhalation of gasoline vapor has inhibitory effects on testicular function leading to decreased serum level of testosterone.";